Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464909 | 0.85 | HPGD (0.43) | RAPGEF4 | |
| SCHEMBL3596270 | 0.75 | MEN1 (0.40) | — | |
| SCHEMBL3959091 | 0.61 | RAPGEF4 (0.40) | RAPGEF4 | |
| SCHEMBL4190358 | 0.60 | — | — | |
| SCHEMBL6231601 | 0.59 | TRPA1 (0.41) | RAPGEF4 | |
| SCHEMBL8447034 | 0.59 | NOS2 (0.47) | — | |
| SCHEMBL11510871 | 0.58 | HTT (0.52) | — | |
| SCHEMBL2544414 | 0.57 | — | — | |
| SCHEMBL5853434 | 0.57 | — | — | |
| SCHEMBL30045340 | 0.57 | IDO1 (0.36) | RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601870-B2 | Such as Hexanoic acid (4-bromo-2,6-dimethyl-phenyl)-amide; potassium channel modulators; epilepsy | H. LUNDBECK A/S (DK) | 2009-10-13 | — | — | US | disclosed |