Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 3/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4193109 | 1.00 | CETP (0.48) | CETPTACR1SORT1CYP11B1CYP11B2 | |
| SCHEMBL4455320 | 1.00 | CETP (0.48) | CETPTACR1SORT1CYP11B1CYP11B2 | |
| SCHEMBL4181225 | 0.89 | CETP (0.45) | CETPTACR1SORT1ADORA2BL3MBTL1 | |
| SCHEMBL4178661 | 0.89 | CETP (0.45) | CETPTACR1SORT1ADORA2BL3MBTL1 | |
| SCHEMBL4185837 | 0.89 | CETP (0.45) | CETPTACR1SORT1ADORA2BL3MBTL1 | |
| SCHEMBL4192558 | 0.85 | SUCNR1 (0.42) | CETPSORT1ADORA2BADORA2AMEN1 | |
| SCHEMBL4187474 | 0.85 | SUCNR1 (0.42) | CETPSORT1ADORA2BADORA2AMEN1 | |
| SCHEMBL4191546 | 0.85 | SUCNR1 (0.42) | CETPSORT1ADORA2BADORA2AMEN1 | |
| SCHEMBL13625387 | 0.83 | CYP11B1 (0.41) | CETPTACR1CYP11B1CYP11B2HDAC4 | |
| SCHEMBL13625412 | 0.82 | MEN1 (0.41) | CETPSORT1ADORA2BHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275515-A1 | 2-HYDROXY-2-PHENYLTHIOPHENYLPROPIONAMIDES AS ANDROGEN RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275515-A1 | 2-HYDROXY-2-PHENYLTHIOPHENYLPROPIONAMIDES AS ANDROGEN RECEPTOR MODULATORS | SHBG, AR, FSHR | CETP 2281/4885TACR1 3877/4885SORT1 3905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.