Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | ALPI | P09923 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14253086 | 0.83 | TSHR (0.52) | NPC1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL12324597 | 0.83 | TSHR (0.52) | NPC1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL14260674 | 0.81 | MAPT (0.71) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL14366502 | 0.81 | L3MBTL1 (0.71) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL14001568 | 0.81 | MAPT (0.71) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL16141030 | 0.81 | MAPT (0.71) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL14020317 | 0.79 | MEN1 (0.48) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL12870014 | 0.77 | ALDH1A1 (0.50) | MEN1KMT2ALMNAL3MBTL1KDM4E | |
| SCHEMBL13283105 | 0.77 | KDM4E (0.41) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL14253085 | 0.77 | KMT2A (0.53) | NPC1RAB9AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3015555-B1 | METHOD FOR AMPLIFYING NUCLEIC ACID | SYSMEX CORP (JP) | 2017-12-20 | — | — | EP | claimed |
| EP-2090304-A2 | Use of sugar phosphates, sugar phosphate analogues, amino acids and/or amino acid analogues for modulating the glycose-enzyme complex, the malate aspartate shuttle and/or transaminases | ScheBo Biotech AG (DE) | 2009-08-19 | — | — | EP | disclosed |
| EP-1368018-A2 | USE OF SUGAR PHOSPHATE, SUGAR PHOSPHATE ANALOGUES, AMINO ACIDS AND/OR AMINO ACID ANALOGUES FOR MODULATING THE GLYCOLYSIS-ENZYME COMPLEX, THE MALATE-ASPARTATE SHUTTLE AND/OR TRANSAMINASES | Schebo Biotech AG (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002072077-A2 | USE OF AMINO ACIDS, AMINO ACID ANALOGUES, SUGAR PHOSPHATES AND SUGAR PHOSPHATE ANALOGUES FOR TREATMENT OF TUMORS, TREATMENT OF SEPSIS AND IMMUNOSUPPRESSION | SCHEBO BIOTECH AG (DE) | 2002-09-19 | — | — | WO | disclosed |
| EP-0138750-B1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED BENZIMIDAZOLES | CIBA-GEIGY AG (CH) | 1987-09-09 | — | — | EP | disclosed |
| EP-0138750-A1 | Process for the production of substituted benzimidazoles | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |