Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CTSV | O60911 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PPIF | P30405 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4471632 | 0.89 | KMT2A (0.51) | EGLN1NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL4468714 | 0.85 | ALDH1A1 (0.50) | EGLN1NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL4468705 | 0.85 | ALDH1A1 (0.50) | EGLN1NPC1MEN1KMT2AALDH1A1 | |
| Aspirin SCHEMBL4461355 | 0.84 | ALDH1A1 (0.52) | EGLN1NPC1MEN1KMT2AALDH1A1 | |
| Aspirin SCHEMBL4461357 | 0.84 | ALDH1A1 (0.52) | EGLN1NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL4461914 | 0.84 | ALDH1A1 (0.58) | EGLN1NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL4465375 | 0.83 | ALDH1A1 (0.53) | EGLN1NPC1MEN1KMT2AALDH1A1 | |
| Salicylic Acid SCHEMBL4456443 | 0.82 | ALDH1A1 (0.64) | EGLN1NPC1MEN1KMT2AALDH1A1 | |
| Salicylic Acid SCHEMBL4456438 | 0.82 | ALDH1A1 (0.64) | EGLN1NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL4460077 | 0.81 | NR4A2 (0.56) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |