SCHEMBL4460077

SCHEMBL4460077

O=C(O)c1cccc(OCc2ccccc2)c1.O=[N+]([O-])c1ccc2cccnc2c1O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 6/20 0.56
MRGPRX4 Q96LA9 2/20 0.51
GPBAR1 Q8TDU6 1/20 0.48
CYSLTR1 Q9Y271 1/20 0.48
SRD5A2 P31213 1/20 0.48
EGLN1 Q9GZT9 1/20 0.47
NR1H4 Q96RI1 1/20 0.47
FFAR1 O14842 1/20 0.47
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4465726 0.88 KMT2A (0.46) NR1H4
M-Phenoxybenzoic Acid For Cis-Isomer SCHEMBL4460165 0.88 KDM4E (0.53) GPBAR1CYSLTR1FFAR1
M-Phenoxybenzoic Acid For Cis-Isomer SCHEMBL4460153 0.88 KDM4E (0.53) GPBAR1CYSLTR1FFAR1
SCHEMBL4466848 0.86 KMT2A (0.56) NR1H4
SCHEMBL4457288 0.86 PLA2G4B (0.52) NR1H4
SCHEMBL4457850 0.84 KMT2A (0.48)
SCHEMBL4460079 0.84 MAPT (0.49) NR4A2MRGPRX4SRD5A2MAOB
Benzoic Acid SCHEMBL4470216 0.83 ALDH1A1 (0.54) EGLN1
Benzoic Acid SCHEMBL4470207 0.83 ALDH1A1 (0.54) EGLN1
SCHEMBL4465370 0.81 EGLN1 (0.53) EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009140215-A2 METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS GERAGHTY, ERIN (US) 2009-11-19 WO claimed
WO-2009140215-A2 METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS GERAGHTY, ERIN (US) 2009-11-19 WO disclosed