Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 15/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465611 | 1.00 | MAOB (0.46) | MAOBGSK3BBACE1MAPK14PTGER1 | |
| SCHEMBL5862277 | 0.90 | GSK3B (0.47) | MAOBGSK3BBACE1MAPK14PTGER1 | |
| SCHEMBL5862284 | 0.84 | MAOB (0.48) | MAOBGSK3BBACE1MAPK14PTGER1 | |
| SCHEMBL4386822 | 0.84 | MAOB (0.48) | MAOBGSK3BBACE1MAPK14 | |
| SCHEMBL3521145 | 0.82 | PTGER1 (0.41) | MAOBGSK3BBACE1MAPK14PTGER1 | |
| SCHEMBL3521142 | 0.82 | PTGER1 (0.41) | MAOBGSK3BBACE1MAPK14PTGER1 | |
| SCHEMBL4389770 | 0.81 | MAPK14 (0.62) | MAPK14 | |
| SCHEMBL4392632 | 0.81 | MAPK14 (0.62) | MAPK14 | |
| SCHEMBL5862282 | 0.80 | MAOB (0.45) | MAOBGSK3BBACE1MAPK14PTGER1 | |
| SCHEMBL6526149 | 0.77 | MAOB (0.53) | MAOBGSK3BBACE1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058964-A1 | Substituted pyridinones | PHARMACIA LLC | 2004-03-25 | — | — | US | claimed |
| US-7629363-B2 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20040058964-A1 | Substituted pyridinones | PHARMACIA LLC | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058964-A1 | Substituted pyridinones | MAPK1, MAPK6, MAPK7 | MAOB 743/4885GSK3B 971/4885BACE1 3069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.