Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9662398 | 0.68 | MAPT (0.36) | MAPTKMT2A | |
| SCHEMBL27638774 | 0.61 | KDM4E (0.40) | MAPTACHEKDM4E | |
| SCHEMBL27566292 | 0.60 | KDM4E (0.36) | MAPTKMT2AKDM4EMEN1CYP1A2 | |
| SCHEMBL28749337 | 0.59 | KDM4E (0.40) | MAPTACHEKDM4E | |
| SCHEMBL11529781 | 0.59 | CA2 (0.34) | MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL3488954 | 0.58 | MAPT (0.36) | MAPTKMT2AMEN1 | |
| SCHEMBL638387 | 0.58 | MAPT (0.36) | MAPTKMT2AMEN1 | |
| SCHEMBL9836851 | 0.58 | POLB (0.36) | MAPTKMT2AKDM4EMEN1CYP1A2 | |
| SCHEMBL8486293 | 0.57 | POLB (0.39) | MAPTKMT2AACHEKDM4EMEN1 | |
| SCHEMBL24980000 | 0.57 | NPC1 (0.40) | KMT2AMEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495101-B2 | Manufacture of vitamin B6 | DSM IP ASSETS B.V. (NL) | 2009-02-24 | — | — | US | disclosed |
| US-20070072254-A1 | Manufacture of vitamin b6 | DSM IP ASSETS B.V. (NL) | 2007-03-29 | — | — | US | disclosed |