Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486234 | 0.90 | POLB (0.42) | POLBALDH1A1GAAKDM4ESMN1; SMN2 | |
| 6,8-Dimethoxy-3,7-Dimethylisochroman SCHEMBL8479086 | 0.85 | ATM (0.41) | ALDH1A1GAAKDM4ESMN1; SMN2DRD1 | |
| SCHEMBL8485301 | 0.85 | ALDH1A1 (0.35) | ALDH1A1GAAKDM4ESMN1; SMN2F3 | |
| SCHEMBL8482088 | 0.83 | F3 (0.39) | ALDH1A1GAAKDM4ESMN1; SMN2F3 | |
| SCHEMBL8485285 | 0.82 | F3 (0.42) | ALDH1A1GAAKDM4EF3CYP3A4 | |
| SCHEMBL8485766 | 0.81 | F3 (0.41) | F3CYP3A4 | |
| SCHEMBL8482079 | 0.80 | KDM4E (0.34) | POLBALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL8482498 | 0.80 | ALDH1A1 (0.40) | ALDH1A1GAAKDM4ESMN1; SMN2DRD1 | |
| 6-Methoxy-3,7-Dimethylisochroman-8-Ol SCHEMBL8484233 | 0.79 | ALDH1A1 (0.40) | POLBALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL8480217 | 0.79 | ALDH1A1 (0.39) | ALDH1A1GAAKDM4ESMN1; SMN2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922889-A | REACTING 3,7-DIMETHYL-6,8-DIMETHOXYISOCHROMAN WITH SODIUM ETHYL THIOLATE OR SODIUM HYDRIDE TO PRODUCE 3,7-DIMETHYL-6-HYDROXY-8-METHOXYISOCHROMAN; POSSESS PHYTOTOXIC ACTIVITY USED AS A BIODEGRADABLE HERBICIDE | THE UNITED STATES OD AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1999-07-13 | — | — | US | disclosed |