SCHEMBL4465774

SCHEMBL4465774

C=Cc1cccc(S)c1S(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
SLC9A1 P19634 2/20 0.35
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1355486 0.86 TDP1 (0.43) TDP1SLC9A1ALDH1A1TSHRSMN1; SMN2
SCHEMBL2543853 0.81 TTR (0.40) TDP1SLC9A1ALDH1A1TSHRSMN1; SMN2
Ammonia Solution, Strong SCHEMBL18492496 0.79 TTR (0.39) TDP1SLC9A1ALDH1A1TSHRSMN1; SMN2
SCHEMBL7774684 0.79 ERN1 (0.39) TDP1SLC9A1ALDH1A1
SCHEMBL167674 0.78 SLC9A1 (0.37) TDP1SLC9A1ALDH1A1TSHRSMN1; SMN2
SCHEMBL28469194 0.78 TTR (0.42) TDP1SLC9A1ALDH1A1TSHRSMN1; SMN2
SCHEMBL8356169 0.78 ALDH1A1 (0.50) TDP1SLC9A1ALDH1A1
SCHEMBL27569612 0.78 ERN1 (0.40) TDP1SLC9A1SMN1; SMN2
SCHEMBL18289495 0.78 TDP1 (0.46) TDP1SLC9A1ALDH1A1TSHRSMN1; SMN2
SCHEMBL7578680 0.76 SLC9A1 (0.36) TDP1SLC9A1ALDH1A1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1524289-B1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2009-09-16 EP disclosed
US-20070149639-A1 Polymerizable composition, optical material comprising the composition and method for producing the material HORIKOSHI HIROSHI 2007-06-28 US disclosed
EP-1524289-A1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-04-20 EP disclosed
US-20040254258-A1 Polymerizable composition, optical material comprising the composition and method for producing the material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2004-12-16 US disclosed