Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1812949 | 0.85 | ACACB (0.49) | MMP2S1PR2S1PR1S1PR3S1PR4 | |
| Hydrochloric Acid SCHEMBL1817481 | 0.84 | ACACB (0.48) | MMP2S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL5598328 | 0.83 | FFAR1 (0.59) | FFAR1FFAR4MMP2MMP12S1PR2 | |
| SCHEMBL2851095 | 0.83 | FFAR1 (0.59) | FFAR1FFAR4MMP2MMP12S1PR2 | |
| SCHEMBL6716853 | 0.81 | FFAR1 (0.58) | FFAR1FFAR4MMP2MMP12S1PR2 | |
| SCHEMBL13708320 | 0.80 | FFAR1 (0.52) | FFAR1FFAR4MMP2MMP12S1PR2 | |
| SCHEMBL5598330 | 0.79 | FFAR1 (0.57) | FFAR1FFAR4MMP2MMP12S1PR2 | |
| SCHEMBL2859750 | 0.78 | FFAR1 (0.85) | FFAR1FFAR4MMP2MMP12S1PR2 | |
| SCHEMBL2855344 | 0.76 | FFAR1 (0.66) | FFAR1FFAR4MMP2MMP12S1PR2 | |
| SCHEMBL2853683 | 0.76 | FFAR1 (0.55) | FFAR1FFAR4MMP2MMP12S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589232-B2 | Alkynyl aryl carboxamides | LABORATORIES SERONO S.A. (CH) | 2009-09-15 | — | — | US | disclosed |
| US-20070105913-A1 | Alkynyl aryl carboxamides | APPLIED RESEARCH SYSTEMS ARS HOLDINGS N.V. (NL) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105913-A1 | Alkynyl aryl carboxamides | ECHS1, IRS1, HCCS | FFAR1 91/4885FFAR4 218/4885MMP2 2103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.