SCHEMBL4466199

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2180488	0.89	P2RX7 (0.50)	P2RX7CNR2
	SCHEMBL4481225	0.87	P2RX7 (0.46)	P2RX7CNR2
	SCHEMBL4461796	0.83	P2RX7 (0.47)	P2RX7CNR2KMT2ASMN1; SMN2
	SCHEMBL4473466	0.83	P2RX7 (0.37)	P2RX7CNR2
	SCHEMBL2180874	0.82	P2RX7 (0.57)	P2RX7CNR2
	SCHEMBL4479948	0.82	CNR2 (0.42)	P2RX7CNR2
	SCHEMBL4460902	0.82	P2RX7 (0.50)	P2RX7CNR2
	SCHEMBL4475495	0.82	P2RX7 (0.57)	P2RX7CNR2SMN1; SMN2
	SCHEMBL2182071	0.81	P2RX7 (0.53)	P2RX7CNR2
	SCHEMBL2182502	0.81	P2RX7 (0.46)	P2RX7CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.