SCHEMBL4479948

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4461695	0.89	P2RX7 (0.41)	CNR2P2RX7CRHR1KCNJ6KCNJ5
	SCHEMBL4461796	0.87	P2RX7 (0.47)	CNR2P2RX7
	SCHEMBL4461741	0.87	P2RX7 (0.50)	CNR2P2RX7CRHR1KCNJ6KCNJ5
	SCHEMBL2180488	0.85	P2RX7 (0.50)	CNR2P2RX7CRHR1
	SCHEMBL4466199	0.82	P2RX7 (0.42)	CNR2P2RX7
	SCHEMBL4481225	0.81	P2RX7 (0.46)	CNR2P2RX7CRHR1
	SCHEMBL4473466	0.81	P2RX7 (0.37)	CNR2P2RX7CRHR1
	SCHEMBL4465128	0.79	P2RX7 (0.58)	CNR2P2RX7
	SCHEMBL4475495	0.78	P2RX7 (0.57)	CNR2P2RX7CRHR1
	SCHEMBL2182071	0.78	P2RX7 (0.53)	CNR2P2RX7CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.