Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.40 |
| ▸ | RAB9A | P51151 | 8/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456549 | 0.89 | RAB9A (0.38) | NPC1RAB9ATNFGAASMN1; SMN2 | |
| SCHEMBL4468908 | 0.82 | NPC1 (0.39) | NPC1RAB9AGAASMN1; SMN2TP53 | |
| SCHEMBL4469735 | 0.73 | RAB9A (0.40) | NPC1RAB9ATNFGAASMN1; SMN2 | |
| SCHEMBL4469739 | 0.73 | RAB9A (0.40) | NPC1RAB9ATNFGAASMN1; SMN2 | |
| SCHEMBL4452847 | 0.72 | RAB9A (0.48) | NPC1RAB9ATNFGAASMN1; SMN2 | |
| SCHEMBL4452838 | 0.72 | RAB9A (0.48) | NPC1RAB9ATNFGAASMN1; SMN2 | |
| SCHEMBL4452906 | 0.72 | RAB9A (0.48) | NPC1RAB9ATNFGAASMN1; SMN2 | |
| SCHEMBL4466206 | 0.71 | KMT2A (0.38) | NPC1RAB9ATNFGAASMN1; SMN2 | |
| SCHEMBL4469855 | 0.70 | RAB9A (0.43) | NPC1RAB9ATNFGAASMN1; SMN2 | |
| SCHEMBL4464061 | 0.70 | RAB9A (0.43) | NPC1RAB9ATNFGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |