Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452847 | 1.00 | RAB9A (0.48) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL4452906 | 1.00 | RAB9A (0.48) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL4469735 | 0.83 | RAB9A (0.40) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL4469739 | 0.83 | RAB9A (0.40) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL4457144 | 0.83 | MEN1 (0.44) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL4457150 | 0.83 | MEN1 (0.44) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL4455255 | 0.82 | RAB9A (0.43) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL4469855 | 0.82 | RAB9A (0.43) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL4464061 | 0.82 | RAB9A (0.43) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL11099522 | 0.79 | NPC1 (0.54) | RAB9ANPC1GAASCDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |