Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4466483 | 1.00 | ALDH1A1 (0.59) | ALDH1A1CTSLCA2CYP1A2CYP3A4 | |
| SCHEMBL4474731 | 1.00 | ALDH1A1 (0.59) | ALDH1A1CTSLCA2CYP1A2CYP3A4 | |
| SCHEMBL4264475 | 0.90 | CTSL (0.67) | ALDH1A1CTSLCA2CYP1A2CYP3A4 | |
| SCHEMBL4264477 | 0.90 | CTSL (0.67) | ALDH1A1CTSLCA2CYP1A2CYP3A4 | |
| SCHEMBL4267852 | 0.90 | CTSL (0.67) | ALDH1A1CTSLCA2CYP1A2CYP3A4 | |
| SCHEMBL12016785 | 0.88 | CTSL (0.58) | ALDH1A1CTSLCA2CYP1A2CYP3A4 | |
| SCHEMBL4457027 | 0.87 | GAA (0.53) | ALDH1A1CTSLCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4457023 | 0.87 | GAA (0.53) | ALDH1A1CTSLCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4467550 | 0.87 | GAA (0.53) | ALDH1A1CTSLCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4460359 | 0.86 | CTSL (0.57) | ALDH1A1CTSLCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042260-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE (S OR R)-ALPHA-AMINO ACID AND OPTICALLY ACTIVE (R OR S)-ALPHA-AMINO ACID ESTER | UBE INDUSTRIES, LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| EP-1942193-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE (S OR R)-a-AMINO ACID OR OPTICALLY ACTIVE (S OR R)-a -AMINO ACID ESTER | Ube Industries, Ltd. (JP) | 2008-07-09 | — | — | EP | disclosed |