Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4475719 | 0.90 | FKBP1A (0.49) | FKBP1AALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL4461070 | 0.88 | CCR4 (0.42) | HPGDSLC6A4HRH3CCR4 | |
| SCHEMBL4556488 | 0.81 | SLC6A4 (0.42) | HPGDSLC6A4HRH3PDK2 | |
| SCHEMBL4329576 | 0.79 | SLC6A4 (0.55) | ALDH1A1KDM4ESLC6A4HRH3 | |
| SCHEMBL4460205 | 0.78 | HRH3 (0.61) | SLC6A4HRH3 | |
| SCHEMBL4326089 | 0.76 | SLC6A4 (0.45) | SLC6A4HRH3 | |
| SCHEMBL4457922 | 0.76 | SLC6A4 (0.42) | ALDH1A1SLC6A4HRH3GAAPDK2 | |
| SCHEMBL4331733 | 0.76 | SLC6A4 (0.46) | SLC6A4HRH3 | |
| SCHEMBL4462029 | 0.75 | SLC6A4 (0.50) | SLC6A4HRH3 | |
| SCHEMBL4338664 | 0.74 | SLC6A4 (0.48) | SLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | claimed |