Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NSD2 | O96028 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12178198 | 0.86 | MEN1 (0.52) | MEN1KMT2AKDM4EMAPTNSD2 | |
| SCHEMBL6901292 | 0.84 | SMN1; SMN2 (0.48) | MEN1KMT2AKDM4EMAPTNSD2 | |
| SCHEMBL11083912 | 0.82 | THRB (0.48) | MEN1KMT2AKDM4EMAPTMCL1 | |
| SCHEMBL13912812 | 0.82 | MEN1 (0.47) | MEN1KMT2AKDM4EMAPTNSD2 | |
| SCHEMBL14753933 | 0.78 | MEN1 (0.40) | MEN1KMT2AKDM4EMAPTNSD2 | |
| SCHEMBL30931542 | 0.77 | MEN1 (0.42) | MEN1KMT2AKDM4EMAPTNSD2 | |
| SCHEMBL30931541 | 0.77 | MEN1 (0.42) | MEN1KMT2AKDM4EMAPTNSD2 | |
| SCHEMBL12803161 | 0.77 | ACHE (0.39) | MEN1KMT2AKDM4EMAPTNSD2 | |
| SCHEMBL5838618 | 0.77 | HSD17B10 (0.50) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL10498460 | 0.76 | MEN1 (0.55) | MEN1KMT2AKDM4EMAPTNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981935-B2 | Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of acids | DSM IP ASSETS B.V. (NL) | 2018-05-29 | — | — | US | disclosed |
| EP-3016939-B1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF ACIDS | DSM IP ASSETS BV (NL) | 2017-03-29 | — | — | EP | disclosed |
| US-20160168110-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF ACIDS | DSM IP ASSETS B.V. (NL) | 2016-06-16 | — | — | US | disclosed |
| EP-3016939-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF ACIDS | DSM IP Assets B.V. (NL) | 2016-05-11 | — | — | EP | disclosed |
| WO-2015001027-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF ACIDS | DSM IP ASSETS B.V. (NL) | 2015-01-08 | — | — | WO | disclosed |
| US-20140031388-A1 | AKT INACTIVATION BY TOCOPHERYL DERIVATIVES | CHEN CHING-SHIH (US) | 2014-01-30 | — | — | US | disclosed |
| EP-2100963-B1 | METHOD OF VITAMIN PRODUCTION | DCV INC (US) | 2011-12-14 | — | — | EP | disclosed |
| EP-2100963-A1 | Method of vitamin production | DCV Inc. doing business as Bio-Technical Resourses (US) | 2009-09-16 | — | — | EP | disclosed |
| US-7576094-B2 | Spiro derivatives as lipoxygenase inhibitors | ELI LILLY AND COMPANY (US) | 2009-08-18 | — | — | US | disclosed |
| EP-1836183-A2 | SPIRO DERIVATIVES AS LIPOXYGENASE INHIBITORS | Galileo Pharmaceuticals, Inc. (US) | 2007-09-26 | — | — | EP | disclosed |
| EP-1095034-A1 | PREPARATION OF TOCOPHEROLS | EASTMAN CHEMICAL COMPANY (US) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001649-A1 | METHOD OF VITAMIN PRODUCTION | DCV, INC. DOING BUSINESS AS BIO-TECHNICAL RESOURCES (US) | 2000-01-13 | — | — | WO | disclosed |
| WO-2000001685-A1 | PREPARATION OF TOCOPHEROLS | EASTMAN CHEMICAL COMPANY (US) | 2000-01-13 | — | — | WO | disclosed |
| US-5318993-A | Antihyperlipidemic benzoquinones | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0443710-B1 | Benzoquinone antiallergy and antiinflammatory agents | PFIZER (US) | 1994-05-11 | — | — | EP | disclosed |
| US-5104874-A | Cyclooxygenase and lipoxygenase inhibitob | PFIZER INC. (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0443710-A1 | Benzoquinone antiallergy and antiinflammatory agents | PFIZER INC. (US) | 1991-08-28 | — | — | EP | disclosed |
| EP-0038092-B1 | PHOTOGRAPHIC MATERIAL SUITED FOR USE IN DIFFUSION TRANSFER PHOTOGRAPHY | AGFA-GEVAERT N.V. (BE) | 1984-03-07 | — | — | EP | disclosed |
| US-4371604-A | Photographic material suited for use in diffusion transfer photography | AGFA-GEVAERT, N.V. (BE) | 1983-02-01 | — | — | US | disclosed |
| EP-0038092-A1 | Photographic material suited for use in diffusion transfer photography | AGFA-GEVAERT N.V. (BE) | 1981-10-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168110-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF ACIDS | CROCC, CBR3, HCCS | MEN1 3257/4885KMT2A 4391/4885KDM4E 3168/4885 |
| US-20140031388-A1 | AKT INACTIVATION BY TOCOPHERYL DERIVATIVES | AKT3, OXSR1, PIK3R1 | MEN1 4546/4885KMT2A 3346/4885KDM4E 830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.