Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | NCEH1 | Q6PIU2 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3873289 | 0.99 | SLC6A4 (0.58) | SLC6A4ACHENCEH1KDM4EALDH1A1 | |
| SCHEMBL3867148 | 0.85 | ACHE (0.61) | SLC6A4ACHEKDM4EALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL3864883 | 0.85 | ACHE (0.61) | SLC6A4ACHEALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL3864660 | 0.85 | ACHE (0.61) | SLC6A4ACHEALDH1A1LMNA | |
| SCHEMBL3873100 | 0.85 | ACHE (0.61) | SLC6A4ACHEALDH1A1KMT2AHTR1D | |
| Hydrochloric Acid SCHEMBL3864955 | 0.84 | ACHE (0.60) | SLC6A4ACHEALDH1A1KMT2AHTR1D | |
| Hydrochloric Acid SCHEMBL3870487 | 0.84 | ACHE (0.60) | SLC6A4ACHEKDM4EALDH1A1KMT2A | |
| SCHEMBL3868464 | 0.82 | ACHE (0.58) | SLC6A4ACHEKDM4EALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL3868025 | 0.82 | ACHE (0.58) | SLC6A4ACHE | |
| Hydrochloric Acid SCHEMBL3863685 | 0.82 | ACHE (0.72) | SLC6A4ACHEALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514475-B2 | Benzylamine analogues | BTG INTERNATIONAL LIMITED (GB) | 2009-04-07 | — | — | US | claimed |