SCHEMBL4468407

SCHEMBL4468407

O=C1C=C(Oc2ccccc2)C(=O)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAPDH P04406 4/20 1.00
CES2 O00748 7/20 0.73
CES1 P23141 7/20 0.73
IDO1 P14902 2/20 0.61
CDC25A P30304 2/20 0.61
CDC25B P30305 2/20 0.61
NSD2 O96028 1/20 0.50
HSP90AA1 P07900 1/20 0.50
HKDC1 Q2TB90 1/20 0.50
TLR9 Q9NR96 1/20 0.50
BACE1 P56817 1/20 0.48
P4HB P07237 1/20 0.48
PTPN1 P18031 1/20 0.47
MEN1 O00255 1/20 0.47
PLIN1 O60240 1/20 0.47
NR1I2 O75469 1/20 0.47
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GSR P00390 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17594909 0.94 GAPDH (0.89) GAPDHCES2CES1IDO1CDC25A
SCHEMBL29647693 0.86 CES1 (0.77) GAPDHCES2CES1IDO1CDC25A
SCHEMBL9849815 0.86 CES2 (0.77) GAPDHCES2CES1IDO1CDC25A
SCHEMBL9628376 0.86 CES1 (0.77) GAPDHCES2CES1IDO1CDC25A
SCHEMBL28916510 0.86 GAPDH (0.75) GAPDHCES2CES1IDO1CDC25A
SCHEMBL9628251 0.86 CES1 (0.77) GAPDHCES2CES1IDO1CDC25A
SCHEMBL17594484 0.86 GAPDH (0.75) GAPDHCES2CES1IDO1CDC25A
SCHEMBL17594358 0.83 GAPDH (0.69) GAPDHCES2CES1IDO1CDC25A
SCHEMBL17594911 0.82 GAPDH (0.70) GAPDHCES2CES1IDO1CDC25A
SCHEMBL9654781 0.82 GAPDH (0.69) GAPDHCES2CES1IDO1CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116875186-A Quick-change color coating for optical lenses and films and preparation method thereof 上海亿乾实业有限公司 2023-10-13 CN claimed
CN-114074464-B Photochromic laminated glass, preparation method and application thereof 上海甘田光学材料有限公司 2022-12-16 CN claimed
CN-114074464-A Photochromic laminated glass, preparation method and application thereof 上海甘田光学材料有限公司 2022-02-22 CN claimed
WO-2016040185-A1 2-(1H-INDAZOL-3-YL)-3H-IMIDAZO[4,5-B]PYRIDINE AND THERAPEUTIC USES THEREOF SAMUMED, LLC (US) 2016-03-17 WO claimed
CN-115948833-B Photochromic ultraviolet-resistant fiber as well as preparation method and application thereof 苏州德扬纺织有限公司 2025-03-07 CN disclosed
CN-119433747-A Photochromic spandex fiber based on sulfhydryl-alkene click reaction and preparation method 湖北省北巷南茂科技有限公司 2025-02-14 CN disclosed
US-20240174589-A1 PHOTOREDOX RADICAL BENZYLATION PROCESS CENTRE NAT RECH SCIENT (FR) 2024-05-30 US disclosed
CN-116875186-A Quick-change color coating for optical lenses and films and preparation method thereof 上海亿乾实业有限公司 2023-10-13 CN disclosed
CN-116875186-A Quick-change color coating for optical lenses and films and preparation method thereof 上海亿乾实业有限公司 2023-10-13 CN disclosed
CN-115948833-A Photochromic anti-ultraviolet fiber and preparation method and application thereof 苏州德扬纺织有限公司 2023-04-11 CN disclosed
CN-113122947-B Multi-base color-changing luminescent fiber with antibacterial property and preparation method thereof 江苏新视界先进功能纤维创新中心有限公司 2022-11-01 CN disclosed
CN-113802208-B Multifunctional transparent nanofiber screen window and preparation method thereof 吉林大学 2022-09-13 CN disclosed
US-5091558-A Topical administeration SYNTEX (U.S.A.) INC. (US) 1992-02-25 US disclosed
US-5089657-A Topical antiinflammatory agents SYNTEX (U.S.A.) INC. (US) 1992-02-18 US disclosed
EP-0410172-A2 2-Halogeno-3-phenoxy-1,4-naphthoquinone derivatives BAYER AG (DE) 1991-01-30 EP disclosed
US-4786652-A TOPICAL ADMINISTRATION SYNTEX (U.S.A.) INC. (US) 1988-11-22 US disclosed
EP-0282006-A1 Naphtalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-09-14 EP disclosed
EP-0282056-A2 Naphthalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-09-14 EP disclosed
US-4758587-A Naphthalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-07-19 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174589-A1 PHOTOREDOX RADICAL BENZYLATION PROCESS H1-2, H1-3, H1-0 GAPDH 3580/4885CES2 1291/4885CES1 2702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.