Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 3/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16857677 | 0.98 | TSHR (0.35) | TSHREPHX1ZDHHC20ZDHHC2THRA | |
| SCHEMBL2744545 | 0.76 | TSHR (0.41) | TSHREPHX1ZDHHC20ZDHHC2THRA | |
| SCHEMBL463179 | 0.75 | — | — | |
| Bromide SCHEMBL28446261 | 0.74 | TSHR (0.40) | TSHREPHX1ZDHHC20ZDHHC2THRA | |
| SCHEMBL2360595 | 0.72 | TSHR (0.37) | TSHREPHX1ZDHHC20ZDHHC2THRA | |
| SCHEMBL9116946 | 0.71 | CA12 (0.42) | TSHRTHRATHRBFAAHCES2 | |
| Hydrochloric Acid SCHEMBL27634971 | 0.71 | TSHR (0.37) | TSHREPHX1ZDHHC20ZDHHC2THRA | |
| SCHEMBL3279930 | 0.68 | KDM5A (0.40) | TSHREPHX1ZDHHC20ZDHHC2THRA | |
| SCHEMBL291199 | 0.67 | DNM1 (0.45) | EPHX1ZDHHC20ZDHHC2FAAHKDM5A | |
| SCHEMBL3280795 | 0.67 | EPHX1 (0.48) | EPHX1ZDHHC20ZDHHC2FAAHKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150114424-A1 | SHAPING AGENT FOR KERATINOUS FIBRES AND HAIR SHAPING METHOD | HENKEL AG & CO. KGAA (DE) | 2015-04-30 | — | — | US | disclosed |
| US-20120060856-A1 | Cosmetic Composition and Reshaping Method for Keratinic Fibers | HENKEL AG & CO. KGAA (DE) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150114424-A1 | SHAPING AGENT FOR KERATINOUS FIBRES AND HAIR SHAPING METHOD | KRT18, COL14A1, COL1A1 | TSHR 3945/4885EPHX1 4175/4885ZDHHC20 17/4885 |
| US-20120060856-A1 | Cosmetic Composition and Reshaping Method for Keratinic Fibers | H1-0, H1-3, H1-2 | TSHR 791/4885EPHX1 1936/4885ZDHHC20 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.