Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.69 |
| ▸ | CLK1 | P49759 | 1/20 | 0.69 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8216740 | 1.00 | GSK3B (0.69) | GSK3BCLK1DYRK1ALMNAMAPT | |
| SCHEMBL4469105 | 1.00 | GSK3B (0.69) | GSK3BCLK1DYRK1ALMNAMAPT | |
| SCHEMBL15421958 | 0.82 | GSK3B (1.00) | GSK3BCLK1DYRK1ALMNAMAPT | |
| SCHEMBL1247645 | 0.82 | GSK3B (1.00) | GSK3BCLK1DYRK1ALMNAMAPT | |
| SCHEMBL1247647 | 0.82 | GSK3B (1.00) | GSK3BCLK1DYRK1ALMNAMAPT | |
| SCHEMBL12821679 | 0.81 | GSK3B (0.81) | GSK3BCLK1DYRK1ALMNAMAPT | |
| SCHEMBL12821680 | 0.81 | GSK3B (0.81) | GSK3BCLK1DYRK1ALMNAMAPT | |
| SCHEMBL15302978 | 0.79 | GSK3B (0.62) | GSK3BCLK1DYRK1ALMNAMAPT | |
| SCHEMBL15302979 | 0.79 | GSK3B (0.62) | GSK3BCLK1DYRK1ALMNAMAPT | |
| SCHEMBL10750988 | 0.76 | GSK3B (0.68) | GSK3BCLK1DYRK1ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188130-B1 | Anti-cancer hydantoin compounds and methods | UNIVERSITY OF LOUISIANA AT MONROE (US) | 2012-05-29 | — | — | US | claimed |
| US-8188130-B1 | Anti-cancer hydantoin compounds and methods | UNIVERSITY OF LOUISIANA AT MONROE (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090029429-A1 | Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1801224-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 2-SUBSTITUENT-OXY-3-(4-SUBSTITUENT-OXYPHENYL)PROPIONIC ACID DERIVATIVE | Kaneka Corporation (JP) | 2007-06-27 | — | — | EP | disclosed |