Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922672 | 1.00 | BRD4 (0.33) | BRD4CREBBPPTAFRAKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL5143995 | 0.99 | BRD4 (0.32) | BRD4CREBBPPTAFR | |
| SCHEMBL1801597 | 0.85 | BRD4 (0.33) | BRD4CREBBPAKR1C3AKR1C2NPC1 | |
| SCHEMBL27757725 | 0.85 | BRD4 (0.34) | BRD4CREBBPLMNA | |
| SCHEMBL7853080 | 0.84 | CHRNB2 (0.32) | BRD4 | |
| SCHEMBL28755381 | 0.84 | BRD4 (0.33) | BRD4CREBBPAKR1C3AKR1C2NPC1 | |
| SCHEMBL7036041 | 0.84 | BRD4 (0.33) | BRD4CREBBPAKR1C3AKR1C2NPC1 | |
| SCHEMBL27663755 | 0.84 | BRD4 (0.33) | BRD4CREBBPAKR1C3AKR1C2NPC1 | |
| Hydrochloric Acid SCHEMBL28755372 | 0.83 | CHRNB2 (0.31) | BRD4 | |
| SCHEMBL28024299 | 0.83 | CHRNB2 (0.31) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101356199-B | Novel bridged metallocene catalyst is used to prepare the method for extra high molecular polymer | TICONA GMBH (DE) | 2015-08-05 | — | — | CN | disclosed |
| US-7569651-B2 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2009-08-04 | — | — | US | disclosed |
| CN-101356199-A | Method for producing ultra-high molecular weight polymers by means of special bridged metallocene catalysts | TICONA GMBH (DE) | 2009-01-28 | — | — | CN | disclosed |
| US-7342078-B2 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2008-03-11 | — | — | US | disclosed |
| US-20060020096-A1 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | SCHOTTEK JORG | 2006-01-26 | — | — | US | disclosed |