Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469130 | 1.00 | BRD4 (0.33) | BRD4CREBBPPTAFRAKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL5143995 | 0.99 | BRD4 (0.32) | BRD4CREBBPPTAFR | |
| SCHEMBL1801597 | 0.85 | BRD4 (0.33) | BRD4CREBBPAKR1C3AKR1C2NPC1 | |
| SCHEMBL27757725 | 0.85 | BRD4 (0.34) | BRD4CREBBPLMNA | |
| SCHEMBL7853080 | 0.84 | CHRNB2 (0.32) | BRD4 | |
| SCHEMBL28755381 | 0.84 | BRD4 (0.33) | BRD4CREBBPAKR1C3AKR1C2NPC1 | |
| SCHEMBL7036041 | 0.84 | BRD4 (0.33) | BRD4CREBBPAKR1C3AKR1C2NPC1 | |
| SCHEMBL27663755 | 0.84 | BRD4 (0.33) | BRD4CREBBPAKR1C3AKR1C2NPC1 | |
| Hydrochloric Acid SCHEMBL28755372 | 0.83 | CHRNB2 (0.31) | BRD4 | |
| SCHEMBL28024299 | 0.83 | CHRNB2 (0.31) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11492425-B2 | Metallocene catalyst compositions and polymerization process therewith | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2022-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492425-B2 | Metallocene catalyst compositions and polymerization process therewith | TERT, MDM4, PCBP1 | BRD4 249/4885CREBBP 2327/4885PTAFR 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.