Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31287197 | 0.87 | ACHE (0.50) | ACHEESR1ESR2GABRA1GABRB1 | |
| SCHEMBL297845 | 0.87 | ACHE (0.50) | ACHEESR1ESR2GABRA1GABRB1 | |
| SCHEMBL296625 | 0.84 | ACHE (0.50) | ACHEESR1ESR2GABRA1GABRB1 | |
| SCHEMBL31287170 | 0.84 | ACHE (0.50) | ACHEESR1ESR2GABRA1GABRB1 | |
| SCHEMBL31287125 | 0.83 | ACHE (0.76) | ACHEESR1ESR2LMNAALOX12 | |
| SCHEMBL10791433 | 0.83 | ACHE (0.76) | ACHEESR1ESR2LMNAALOX12 | |
| SCHEMBL297912 | 0.83 | ACHE (0.76) | ACHEESR1ESR2LMNAALOX12 | |
| SCHEMBL4564678 | 0.82 | ACHE (0.37) | ACHEGABRA1GABRB1 | |
| SCHEMBL297822 | 0.80 | ACHE (0.76) | ACHEESR1ESR2LMNASLC6A2 | |
| SCHEMBL10787766 | 0.80 | ACHE (0.76) | ACHEESR1ESR2LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984472-B1 | POLYCARBONATE COMPOSITIONS AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP (NL) | 2009-11-18 | — | — | EP | disclosed |