SCHEMBL4469310

SCHEMBL4469310

c1cc2ccc3ccc(-c4ccc(-c5cn6cccnc6n5)cc4)c4ccc(c1)c2c34

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 14/20 0.58
▸ KDM4E B2RXH2 13/20 0.58
▸ HPGD P15428 8/20 0.58
▸ GLA P06280 6/20 0.58
▸ HSD17B10 Q99714 4/20 0.58
▸ RAB9A P51151 13/20 0.58
▸ NPC1 O15118 11/20 0.58
▸ GAA P10253 9/20 0.58
▸ SMN1; SMN2 Q16637 7/20 0.58
▸ MAPT P10636 5/20 0.58
▸ KMT2A Q03164 4/20 0.58
▸ MEN1 O00255 3/20 0.58
▸ TP53 P04637 2/20 0.58
▸ POLB P06746 2/20 0.54
▸ GFER P55789 1/20 0.51
▸ CYP1A2 P05177 1/20 0.49
▸ CDC7 O00311 1/20 0.46
▸ DAPK3 O43293 1/20 0.46
▸ DYRK3 O43781 1/20 0.46
▸ ROCK2 O75116 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15803051 0.86 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL15803090 0.82 RAB9A (0.49) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL15803103 0.82 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL16622282 0.81 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL16622263 0.81 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL15803105 0.81 ALDH1A1 (0.48) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL25112792 0.81 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL12731457 0.80 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL25112805 0.80 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL12731474 0.80 ALDH1A1 (0.49) ALDH1A1KDM4EHPGDGLAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2157627-B1 Organic light emitting diode including light-efficiency-improvement layer SAMSUNG DISPLAY CO LTD (KR) 2013-01-23 — — EP disclosed
US-8343638-B2 Organic light emitting diode including light-efficiency-improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2013-01-01 — — US disclosed
US-8343638-B2 Organic light emitting diode including light-efficiency-improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2013-01-01 — — US disclosed
EP-2157627-A1 Organic light emitting diode including light-efficiency-improvement layer Samsung Mobile Display Co., Ltd. (KR) 2010-02-24 — — EP disclosed
US-20100039029-A1 Organic Light Emitting Diode Including Light-Efficiency-Improvement Layer SAMSUNG DISPLAY CO., LTD. (KR) 2010-02-18 — — US disclosed
US-20100039029-A1 Organic Light Emitting Diode Including Light-Efficiency-Improvement Layer SAMSUNG DISPLAY CO., LTD. (KR) 2010-02-18 — — US disclosed
US-20090153035-A1 Heteroaromatic cycle-containing compound, method of preparing the same and organic light emitting device comprising the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2009-06-18 — — US disclosed
US-20090153035-A1 Heteroaromatic cycle-containing compound, method of preparing the same and organic light emitting device comprising the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2009-06-18 — — US disclosed
US-20090153035-A1 Heteroaromatic cycle-containing compound, method of preparing the same and organic light emitting device comprising the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2009-06-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090153035-A1 Heteroaromatic cycle-containing compound, method of preparing the same and organic light emitting device comprising the same CCNE2, CCNC, CCNT1 ALDH1A1 337/4885KDM4E 2044/4885HPGD 1572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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