Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 5/20 | 0.53 |
| ▸ | APAF1 | O14727 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | MC4R | P32245 | 2/20 | 0.53 |
| ▸ | UBE2N | P61088 | 2/20 | 0.53 |
| ▸ | RAD52 | P43351 | 2/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469449 | 1.00 | MEN1 (0.58) | MEN1KMT2AALDH1A1USP2APAF1 | |
| Iodide SCHEMBL1774984 | 0.99 | MEN1 (0.57) | MEN1KMT2AALDH1A1USP2APAF1 | |
| Iodide SCHEMBL1774982 | 0.99 | MEN1 (0.57) | MEN1KMT2AALDH1A1USP2APAF1 | |
| SCHEMBL3939116 | 0.89 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1USP2APAF1 | |
| SCHEMBL12604820 | 0.88 | MEN1 (0.74) | MEN1KMT2AALDH1A1USP2APAF1 | |
| SCHEMBL12604821 | 0.88 | MEN1 (0.61) | MEN1KMT2AALDH1A1USP2APAF1 | |
| Iodide SCHEMBL1775221 | 0.87 | MEN1 (0.60) | MEN1KMT2AALDH1A1USP2APAF1 | |
| Iodide SCHEMBL1776114 | 0.87 | MEN1 (0.73) | MEN1KMT2AALDH1A1USP2APAF1 | |
| Iodide SCHEMBL1776111 | 0.87 | MEN1 (0.73) | MEN1KMT2AALDH1A1USP2APAF1 | |
| Iodide SCHEMBL1775222 | 0.87 | MEN1 (0.60) | MEN1KMT2AALDH1A1USP2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589083-B2 | [3-(3,4-Dimethyl-9-oxo-9H- thioxanthen-2-yloxy)-2- hydroxypropyl]trimethyl- ammonium chloride; antitumor; simultaneously enhancing the efficacy and decreasing the toxicity of chemotherapy by single agents | CANCURE LABORATORIES, LLC (US) | 2009-09-15 | — | — | US | disclosed |
| US-20070060634-A1 | COMPOUNDS AND COMPOSITIONS TO CONTROL ABNORMAL CELL GROWTH | ZOLTAN LABORATORIES LLC (US) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060634-A1 | COMPOUNDS AND COMPOSITIONS TO CONTROL ABNORMAL CELL GROWTH | ALPP, DNTT, ALPG | MEN1 3192/4885KMT2A 771/4885ALDH1A1 2158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.