Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NCS1 | P62166 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457403 | 0.88 | NPC1 (0.46) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4457405 | 0.88 | NPC1 (0.46) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4456576 | 0.84 | ADORA1 (0.46) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4456572 | 0.84 | ADORA1 (0.46) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4456590 | 0.83 | ADORA1 (0.52) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4454870 | 0.83 | ADORA1 (0.52) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4469855 | 0.75 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1CSNK1D | |
| SCHEMBL4455255 | 0.75 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1CSNK1D | |
| SCHEMBL4464061 | 0.75 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1CSNK1D | |
| SCHEMBL383066 | 0.75 | NPC1 (0.59) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |