Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464061 | 1.00 | RAB9A (0.43) | RAB9ANPC1GAASCDTNF | |
| SCHEMBL4469855 | 1.00 | RAB9A (0.43) | RAB9ANPC1GAASCDTNF | |
| SCHEMBL4466206 | 0.85 | KMT2A (0.38) | RAB9ANPC1GAASCDTNF | |
| SCHEMBL4456544 | 0.85 | KMT2A (0.43) | RAB9ANPC1GAASCDTNF | |
| SCHEMBL4452838 | 0.82 | RAB9A (0.48) | RAB9ANPC1GAASCDTNF | |
| SCHEMBL4452847 | 0.82 | RAB9A (0.48) | RAB9ANPC1GAASCDTNF | |
| SCHEMBL4452906 | 0.82 | RAB9A (0.48) | RAB9ANPC1GAASCDTNF | |
| SCHEMBL4469745 | 0.75 | ADORA1 (0.48) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL16972931 | 0.74 | NPC1 (0.54) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL11099522 | 0.74 | NPC1 (0.54) | RAB9ANPC1GAASCDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |