Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | METAP2 | P50579 | 5/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4319911 | 0.88 | ATM (0.33) | KDM4EMAPTMETAP2METAP1SLC6A4 | |
| SCHEMBL4319928 | 0.78 | SLC6A2 (0.46) | SLC6A4SLC6A2SLC6A3SMN1; SMN2CHRM3 | |
| SCHEMBL4326074 | 0.70 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4470550 | 0.68 | KDM4E (0.41) | KDM4EMAPTSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27360664 | 0.62 | MAPT (0.42) | KDM4EMAPTMETAP2METAP1SLC6A2 | |
| SCHEMBL5275095 | 0.61 | KDM4E (0.56) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10188356 | 0.61 | MAOA (0.53) | KDM4EMAPTSLC6A4SLC6A2CHRM3 | |
| SCHEMBL17121327 | 0.61 | KDM4E (0.51) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6938817 | 0.61 | KDM4E (0.50) | KDM4EMETAP2METAP1ALDH1A1EPHX1 | |
| SCHEMBL21369339 | 0.61 | DRD2 (0.55) | KDM4ESLC6A4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |