Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 5/20 | 0.32 |
| ▸ | METAP1 | P53582 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 4/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4463813 | 0.88 | KDM4E (0.39) | KDM4EMAPTALDH1A1GLAGAA | |
| SCHEMBL4470550 | 0.86 | KDM4E (0.41) | ATML3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL4319928 | 0.69 | SLC6A2 (0.46) | CHRM3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4454609 | 0.65 | SLC6A2 (0.53) | CHRM3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4476207 | 0.60 | SLC6A2 (0.47) | CHRM3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21142183 | 0.56 | CYP2B6 (0.46) | ATML3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL28188331 | 0.56 | ALDH1A1 (0.42) | KDM4EMAPTALDH1A1GAASLC6A2 | |
| SCHEMBL9906166 | 0.56 | KEAP1 (0.56) | ATML3MBTL1MAPTCHRM3 | |
| SCHEMBL13131231 | 0.56 | KEAP1 (0.56) | ATML3MBTL1MAPTCHRM3 | |
| SCHEMBL18415154 | 0.56 | KEAP1 (0.56) | ATML3MBTL1MAPTCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | claimed |