Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29543098 | 0.98 | TDP1 (0.58) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL118554 | 0.98 | TDP1 (0.58) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| Ethane SCHEMBL9117335 | 0.97 | TDP1 (0.56) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| Methane SCHEMBL10458377 | 0.97 | TDP1 (0.56) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL28231741 | 0.90 | TDP1 (0.68) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| Ronnel SCHEMBL6832096 | 0.86 | TDP1 (0.51) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| Ronnel SCHEMBL6736758 | 0.84 | TDP1 (0.53) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| Ronnel SCHEMBL11879973 | 0.84 | TDP1 (0.53) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| Ronnel SCHEMBL3272218 | 0.84 | TDP1 (0.53) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| Ronnel SCHEMBL29375404 | 0.84 | TDP1 (0.53) | TDP1ALDH1A1CYP3A4MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531393-B2 | Non-planar MOS structure with a strained channel region | INTEL CORPORATION (US) | 2009-05-12 | — | — | US | disclosed |
| US-7193279-B2 | Non-planar MOS structure with a strained channel region | INTEL CORPORATION (US) | 2007-03-20 | — | — | US | disclosed |
| WO-2006078469-A1 | NON-PLANAR MOS STRUCTURE WITH A STRAINED CHANNEL REGION | INTEL CORPORATION (US) | 2006-07-27 | — | — | WO | disclosed |
| US-20060157794-A1 | Non-planar MOS structure with a strained channel region | DOYLE BRIAN S | 2006-07-20 | — | — | US | disclosed |
| US-20060157687-A1 | Non-planar MOS structure with a strained channel region | INTEL CORPORATION | 2006-07-20 | — | — | US | disclosed |