SCHEMBL4470668

SCHEMBL4470668

C=C[SiH2]OCCCCCCCCCCCCCCCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
THRB P10828 2/20 0.36
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPT P10636 1/20 0.35
LPAR3 Q9UBY5 5/20 0.34
CA1 P00915 5/20 0.34
CA2 P00918 5/20 0.34
CA9 Q16790 5/20 0.34
LPAR2 Q9HBW0 4/20 0.34
LPAR1 Q92633 2/20 0.34
NAAA Q02083 1/20 0.34
CA12 O43570 1/20 0.34
CA3 P07451 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA14 Q9ULX7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10847637 1.00 TSHR (0.41) TSHRTHRBMEN1HTTKMT2A
SCHEMBL31152655 1.00 TSHR (0.41) TSHRTHRBMEN1HTTKMT2A
SCHEMBL14633833 0.98
SCHEMBL6275468 0.91
SCHEMBL3482073 0.80
SCHEMBL10579968 0.74 LPAR3 (0.38) TSHRTHRBMEN1HTTKMT2A
SCHEMBL15266070 0.74 TSHR (0.43) TSHRTHRBMEN1HTTKMT2A
SCHEMBL8769921 0.72 THRB (0.47) TSHRTHRBMEN1HTTKMT2A
SCHEMBL8769324 0.72 THRB (0.47) TSHRTHRBMEN1HTTKMT2A
SCHEMBL27462289 0.72 THRB (0.47) TSHRTHRBMEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2035473-A1 SOLUTIONS CONTAINING SOLIDS OF SILICONORGANOCOPOLYMERS WITH HIGHT SILICON CONTENT AND HIGH SOLID CONENT AND METHOD FOR THE PRODUCTION AND THE USE THEREOF Wacker Chemie AG (DE) 2009-03-18 EP disclosed
WO-2008017672-A1 SOLUTIONS CONTAINING SOLIDS OF SILICONORGANOCOPOLYMERS WITH HIGHT SILICON CONTENT AND HIGH SOLID CONENT AND METHOD FOR THE PRODUCTION AND THE USE THEREOF WACKER CHEMIE AG (DE) 2008-02-14 WO disclosed