Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.62 |
| ▸ | PYGL | P06737 | 2/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13864630 | 0.88 | KDM4E (0.61) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL4484324 | 0.88 | KDM4E (0.64) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL4460774 | 0.88 | KDM4E (0.64) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL4460803 | 0.86 | KDM4E (0.59) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL4465153 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL13867216 | 0.86 | KDM4E (0.56) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL4461598 | 0.85 | ALDH1A1 (0.58) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL13864726 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL14512076 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL4466439 | 0.85 | SMN1; SMN2 (0.58) | KDM4EALDH1A1CYP1A2CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531668-B2 | 2-arylcarboxamide-nitrogenous heterocycle compound | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-05-12 | — | — | US | disclosed |
| US-20070299070-A1 | 2-Arylcarboxamide-Nitrogenous Heterocycle Compound | MSD K.K. (JP) | 2007-12-27 | — | — | US | disclosed |
| EP-1798221-A1 | 2-ARYLCARBOXAMIDE-NITROGENEOUS HETEROCYCLE COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299070-A1 | 2-Arylcarboxamide-Nitrogenous Heterocycle Compound | MCHR2, MCHR1, NPY2R | KDM4E 2454/4885ALDH1A1 1060/4885CYP1A2 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.