SCHEMBL4466439

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4461598	0.99	ALDH1A1 (0.58)	SMN1; SMN2LMNAALDH1A1HTTMEN1
	Trifluoroacetic Acid SCHEMBL4474703	0.95	SMN1; SMN2 (0.53)	SMN1; SMN2LMNAALDH1A1HTTMEN1
	Trifluoroacetic Acid SCHEMBL4466676	0.94	KDM4E (0.52)	SMN1; SMN2LMNAALDH1A1HTTMEN1
	SCHEMBL4480562	0.91	ALDH1A1 (0.55)	SMN1; SMN2LMNAALDH1A1HTTMEN1
	Hydrochloric Acid SCHEMBL4466303	0.90	ALDH1A1 (0.54)	SMN1; SMN2LMNAALDH1A1HTTMEN1
	SCHEMBL4464567	0.89	ACHE (0.53)	SMN1; SMN2LMNAALDH1A1HTTKDM4E
	Trifluoroacetic Acid SCHEMBL4465727	0.85	ACHE (0.51)	SMN1; SMN2LMNAALDH1A1HTTKDM4E
	SCHEMBL4470715	0.85	KDM4E (0.66)	SMN1; SMN2LMNAALDH1A1KDM4ECYP1A2
	SCHEMBL13864630	0.81	KDM4E (0.61)	SMN1; SMN2ALDH1A1KDM4ECYP1A2CYP2C9
	SCHEMBL4460774	0.81	KDM4E (0.64)	SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.