Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 7/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4492028 | 0.82 | CYP2A6 (0.50) | CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL11238966 | 0.82 | CYP2A6 (0.51) | CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL25871455 | 0.80 | CYP2A6 (0.42) | CYP2A6CYP3A4CYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL15984789 | 0.79 | CYP17A1 (0.38) | CYP2A6CYP3A4CYP2C9CYP2C19NPC1 | |
| SCHEMBL2472468 | 0.78 | CYP2A6 (0.53) | CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL16279826 | 0.78 | CYP2A6 (0.53) | CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL31372554 | 0.78 | CYP2A6 (0.53) | CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL10262765 | 0.78 | PSMB5 (0.47) | CYP2A6CYP2C9CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL5320803 | 0.77 | CYP3A4 (0.55) | CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL10205407 | 0.77 | CYP2A6 (0.56) | CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3923363-A1 | ORGANIC LIGHT EMITTING DIODE AND DEVICE COMPRISING THE SAME | Novaled GmbH (DE) | 2021-12-15 | — | — | EP | disclosed |
| US-7579353-B2 | Pyridinone derivatives against malaria | GLAXO GROUP LIMITED (GB) | 2009-08-25 | — | — | US | disclosed |
| US-20080287461-A1 | Pyridinone Derivatives Against Malaria | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287461-A1 | Pyridinone Derivatives Against Malaria | G6PD, PNPO, PLPBP | CYP2A6 108/4885CYP3A4 5/4885CYP2E1 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.