Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.49 |
| ▸ | LPAR4 | Q99677 | 4/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227658 | 0.94 | MAPT (0.56) | MAPTL3MBTL1CRHBPCRHR2CNR2 | |
| SCHEMBL4460728 | 0.94 | MAPT (0.56) | MAPTL3MBTL1CRHBPCRHR2CNR2 | |
| SCHEMBL4471285 | 0.94 | MAPT (0.56) | MAPTL3MBTL1CRHBPCRHR2CNR2 | |
| SCHEMBL5038535 | 0.93 | MAPT (0.54) | MAPTL3MBTL1CRHBPCRHR2CNR2 | |
| SCHEMBL4457525 | 0.81 | MAPT (0.56) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL6024458 | 0.81 | ALDH1A1 (0.62) | DGKAMAPTL3MBTL1CRHBPCRHR2 | |
| SCHEMBL9615216 | 0.81 | BCL9 (0.57) | MAPTL3MBTL1ALDH1A1TDP1MGLL | |
| SCHEMBL14515276 | 0.80 | MAPT (0.50) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL23117008 | 0.79 | MAPT (0.48) | FAAHMAPTL3MBTL1CRHBPCRHR2 | |
| SCHEMBL11761443 | 0.79 | BCL9 (0.67) | ALDH1A1TDP1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595181-B2 | From thermophilic microorganisms; active at high temperature | PROTEUS S.A. (FR) | 2009-09-29 | — | — | US | claimed |
| US-7595181-B2 | From thermophilic microorganisms; active at high temperature | PROTEUS S.A. (FR) | 2009-09-29 | — | — | US | disclosed |
| EP-1668124-A2 | THERMOSTABLE HYDROLASE | Goldschmidt GmbH (DE) | 2006-06-14 | — | — | EP | disclosed |
| US-20060008887-A1 | Production of carboxylic acid and carbonic acid derivatives using a thermostable esterase | GOLDSCHMIDT AG (DE) | 2006-01-12 | — | — | US | disclosed |
| US-20050112644-A1 | Thermostable hydrolase | EVONIK GOLDSCHMIDT GMBH (DE) | 2005-05-26 | — | — | US | disclosed |
| WO-2005040370-A2 | THERMOSTABLE HYDROLASE | GOLDSCHMIDT GMBH (DE) | 2005-05-06 | — | — | WO | disclosed |