Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | P2RY10 | O00398 | 2/20 | 0.44 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460728 | 1.00 | MAPT (0.56) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL4471285 | 1.00 | MAPT (0.56) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL5038535 | 0.99 | MAPT (0.54) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL4471290 | 0.94 | DGKA (0.54) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL4457525 | 0.86 | MAPT (0.56) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL6024458 | 0.86 | ALDH1A1 (0.62) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL14515253 | 0.81 | MAPT (0.55) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL14515255 | 0.81 | MAPT (0.55) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL11664047 | 0.81 | MAPT (0.55) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL14515276 | 0.80 | MAPT (0.50) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595181-B2 | From thermophilic microorganisms; active at high temperature | PROTEUS S.A. (FR) | 2009-09-29 | — | — | US | claimed |
| EP-1727909-B1 | METHOD AND TEST-KIT FOR THE DETECTION AND QUANTIFICATION OF ORGANISMS | EVONIK GOLDSCHMIDT GMBH (DE) | 2008-12-10 | — | — | EP | claimed |
| US-20070264680-A1 | Method and Test-Kit for the Detection and Quantification of Organisms | PROTEUS S.A. (FR) | 2007-11-15 | — | — | US | claimed |
| EP-1727909-A1 | METHOD AND TEST-KIT FOR THE DETECTION AND QUANTIFICATION OF ORGANISMS | Goldschmidt GmbH (DE) | 2006-12-06 | — | — | EP | claimed |
| US-20060008887-A1 | Production of carboxylic acid and carbonic acid derivatives using a thermostable esterase | GOLDSCHMIDT AG (DE) | 2006-01-12 | — | — | US | claimed |
| WO-2005093089-A1 | METHOD AND TEST-KIT FOR THE DETECTION AND QUANTIFICATION OF ORGANISMS | GOLDSCHMIDT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG (DE) | 2005-10-06 | — | — | WO | claimed |
| US-20120295793-A1 | METHODS OF GENERATING MODIFIED POLYNUCLEOTIDE LIBRARIES AND METHODS OF USING THE SAME FOR DIRECTED PROTEIN EVOLUTION | PROTEUS (FR) | 2012-11-22 | — | — | US | disclosed |
| WO-2011089574-A2 | METHODS OF GENERATING MODIFIED POLYNUCLEOTIDE LIBRARIES AND METHODS OF USING THE SAME FOR DIRECTED PROTEIN EVOLUTION | PROTEUS (FR) | 2011-07-28 | — | — | WO | disclosed |
| US-7595181-B2 | From thermophilic microorganisms; active at high temperature | PROTEUS S.A. (FR) | 2009-09-29 | — | — | US | disclosed |
| EP-1727909-B1 | METHOD AND TEST-KIT FOR THE DETECTION AND QUANTIFICATION OF ORGANISMS | EVONIK GOLDSCHMIDT GMBH (DE) | 2008-12-10 | — | — | EP | disclosed |
| US-20070264680-A1 | Method and Test-Kit for the Detection and Quantification of Organisms | PROTEUS S.A. (FR) | 2007-11-15 | — | — | US | disclosed |
| EP-1727909-A1 | METHOD AND TEST-KIT FOR THE DETECTION AND QUANTIFICATION OF ORGANISMS | Goldschmidt GmbH (DE) | 2006-12-06 | — | — | EP | disclosed |
| US-20060198859-A1 | Compositions with a depot effect for controlling microorganisms | GOLDSCHMIDT GMBH (DE) | 2006-09-07 | — | — | US | disclosed |
| EP-1668124-A2 | THERMOSTABLE HYDROLASE | Goldschmidt GmbH (DE) | 2006-06-14 | — | — | EP | disclosed |
| US-20060008887-A1 | Production of carboxylic acid and carbonic acid derivatives using a thermostable esterase | GOLDSCHMIDT AG (DE) | 2006-01-12 | — | — | US | disclosed |
| WO-2005093089-A1 | METHOD AND TEST-KIT FOR THE DETECTION AND QUANTIFICATION OF ORGANISMS | GOLDSCHMIDT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG (DE) | 2005-10-06 | — | — | WO | disclosed |
| US-20050112644-A1 | Thermostable hydrolase | EVONIK GOLDSCHMIDT GMBH (DE) | 2005-05-26 | — | — | US | disclosed |
| WO-2005040370-A2 | THERMOSTABLE HYDROLASE | GOLDSCHMIDT GMBH (DE) | 2005-05-06 | — | — | WO | disclosed |