Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.71 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PDE2A | O00408 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MAT2A | P31153 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030743 | 0.86 | SIRT2 (0.71) | SIRT2SIRT1ALDH1A1MAPTKDM4E | |
| SCHEMBL4482921 | 0.84 | SIRT2 (0.68) | SIRT2SIRT1ALDH1A1MAPTKDM4E | |
| SCHEMBL1356532 | 0.82 | ALOX15 (0.50) | SIRT2SIRT1ALDH1A1MAPTKDM4E | |
| SCHEMBL4485382 | 0.78 | PTGER4 (0.58) | SIRT2SIRT1ALDH1A1MAPTKDM4E | |
| SCHEMBL12374638 | 0.78 | KDM4E (0.52) | SIRT2SIRT1ALDH1A1MAPTKDM4E | |
| SCHEMBL30343744 | 0.76 | FGFR1 (0.75) | SIRT2SIRT1ALDH1A1HPGDNPC1 | |
| SCHEMBL541343 | 0.75 | HSD17B10 (0.76) | SIRT2SIRT1ALDH1A1MAPTKDM4E | |
| SCHEMBL17456641 | 0.75 | KDM4E (0.59) | SIRT2SIRT1ALDH1A1MAPTKDM4E | |
| SCHEMBL2162546 | 0.74 | MEN1 (0.61) | SIRT2SIRT1ALDH1A1MAPTKDM4E | |
| SCHEMBL21760759 | 0.74 | SIRT2 (0.74) | SIRT2SIRT1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009116074-A2 | SUBSTITUTED BENZIMIDAZOLES AS CANNABINOID MODULATOR | CADILA HEALTHCARE LIMITED (IN) | 2009-09-24 | — | — | WO | disclosed |