Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4482058 | 0.79 | PTGER4 (0.57) | PTGER4ALDH1A1HPGDSIRT2SIRT1 | |
| SCHEMBL4471406 | 0.78 | SIRT2 (0.71) | ALDH1A1HPGDSIRT2SIRT1NPC1 | |
| SCHEMBL4728865 | 0.77 | ATM (0.55) | PTGER4ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL14800136 | 0.75 | KDM4E (0.58) | ALDH1A1SIRT2SIRT1NPC1RAB9A | |
| SCHEMBL6172359 | 0.74 | SMN1; SMN2 (0.48) | PTGER4ALDH1A1HPGDSIRT2SIRT1 | |
| SCHEMBL17938339 | 0.74 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL14800064 | 0.74 | KDM4E (0.80) | ALDH1A1HPGDSIRT2SIRT1NPC1 | |
| SCHEMBL28382487 | 0.73 | NPC1 (0.56) | PTGER4ALDH1A1HPGDSIRT2SIRT1 | |
| SCHEMBL1537629 | 0.73 | KDM4E (0.40) | ALDH1A1HPGDRAB9AMEN1KMT2A | |
| SCHEMBL14800591 | 0.73 | ALDH1A1 (0.48) | PTGER4ALDH1A1HPGDSIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009116074-A2 | SUBSTITUTED BENZIMIDAZOLES AS CANNABINOID MODULATOR | CADILA HEALTHCARE LIMITED (IN) | 2009-09-24 | — | — | WO | disclosed |