Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | SI | P14410 | 4/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397623 | 0.87 | PKM (0.54) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3130750 | 0.87 | PKM (0.51) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9215783 | 0.86 | PKM (0.59) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6284347 | 0.86 | KMT2A (0.61) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27411615 | 0.85 | MGAM (0.47) | PKMMAPTKDM4EKMT2AGPR84 | |
| SCHEMBL27440110 | 0.85 | MGAM (0.47) | PKMMAPTKDM4EKMT2AGPR84 | |
| SCHEMBL9584209 | 0.83 | PKM (0.55) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL21954272 | 0.83 | MGAM (0.46) | PKMMAPTKDM4EKMT2AGPR84 | |
| SCHEMBL8387335 | 0.83 | PKM (0.55) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11228195 | 0.82 | PKM (0.54) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042260-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE (S OR R)-ALPHA-AMINO ACID AND OPTICALLY ACTIVE (R OR S)-ALPHA-AMINO ACID ESTER | UBE INDUSTRIES, LTD. (JP) | 2009-02-12 | — | — | US | disclosed |