Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | SI | P14410 | 4/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215783 | 0.86 | PKM (0.59) | KMT2APKMSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL4471722 | 0.86 | PKM (0.59) | KMT2APKMSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL6286142 | 0.86 | KMT2A (0.51) | KMT2APKMMAPTALDH1A1GPR84 | |
| SCHEMBL8387335 | 0.83 | PKM (0.55) | KMT2APKMSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL6288442 | 0.83 | KMT2A (0.48) | KMT2APKMMAPTGPR84MGAM | |
| SCHEMBL7397623 | 0.82 | PKM (0.54) | KMT2APKMSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL11228195 | 0.82 | PKM (0.54) | KMT2APKMSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL6287075 | 0.82 | KMT2A (0.58) | KMT2APKMSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL6288559 | 0.80 | MGAM (0.57) | KMT2APKMSMN1; SMN2MAPTGPR84 | |
| SCHEMBL9618447 | 0.79 | PKM (0.67) | KMT2APKMSMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911468-B2 | Tyrosine phosphatase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-06-28 | — | — | US | disclosed |
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1284260-A1 | TYROSINE PHOSPHATASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | PTPRC, PTPN1, PTPRM | KMT2A 629/4885PKM 2978/4885SMN1; SMN2 4638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.