Hydrochloric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ACHE BDKRB2 CHRM1 CHRM2 CHRM3 CHRNA1 CHRNB1 CHRND CHRNE CHRNG GUCY1A1 GUCY1A2 GUCY1B1 GUCY1B2 NAMPT PTAFR SLC10A2 SLC6A2 SLC6A3 TACR1 dacA dacB dacC ftsI mrcA mrcB mrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	HTR6	P50406	1/20	0.37

▸	SIGMAR1	Q99720	6/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Hydrochloric Acid SCHEMBL4469083	0.91	HTR6 (0.36)	HTR6SIGMAR1
Hydrochloric Acid SCHEMBL4470100	0.84	HTR6 (0.38)	HTR6SIGMAR1
Hydrochloric Acid SCHEMBL4479298	0.76	HTR6 (0.41)	HTR6SIGMAR1
SCHEMBL5039095	0.76	HTR6 (0.43)	HTR6SIGMAR1
Hydrochloric Acid SCHEMBL6061908	0.75	HTR6 (0.38)	HTR6SIGMAR1
SCHEMBL4475036	0.75	HTR6 (0.42)	HTR6SIGMAR1
SCHEMBL671513	0.74	HTR6 (0.46)	HTR6SIGMAR1
Hydrochloric Acid SCHEMBL4476299	0.73	HTR6 (0.43)	HTR6SIGMAR1
SCHEMBL4479300	0.72	HTR6 (0.40)	HTR6SIGMAR1
Hydrochloric Acid SCHEMBL4466028	0.72	HTR6 (0.40)	HTR6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1671983-B1	Catalysts compositions for the polymerization and copolymerization of alpha-olefins	REPSOL QUIMICA SA (ES)	2009-02-25	—	—	EP	claimed