Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | IL2 | P60568 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743593 | 0.85 | HTT (0.49) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL14743510 | 0.85 | HTT (0.49) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL471858 | 0.83 | KDM4E (0.60) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL20411007 | 0.82 | HRH3 (0.54) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL19379609 | 0.81 | KDM4E (0.47) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL471881 | 0.80 | KDM4E (0.62) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL20409590 | 0.80 | KDM4E (0.53) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL9368268 | 0.80 | MAPT (0.50) | HTTLMNAMAPTKDM4EHRH3 | |
| SCHEMBL19379596 | 0.80 | LMNA (0.44) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL18380643 | 0.80 | KDM4E (0.61) | HTTLMNAMAPTKDM4EHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592741-B1 | STABILIZATION OF THERMOPLASTIC NANOCOMPOSITES | CIBA HOLDING INC (CH) | 2009-01-14 | — | — | EP | disclosed |
| EP-1592741-A1 | STABILIZATION OF THERMOPLASTIC NANOCOMPOSITES | Ciba SC Holding AG (CH) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004063268-A1 | STABILIZATION OF THERMOPLASTIC NANOCOMPOSITES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-07-29 | — | — | WO | disclosed |
| EP-0785967-B1 | INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES | CIBA SC HOLDING AG (CH) | 2002-01-09 | — | — | EP | disclosed |
| US-5807932-A | USING A HYDROXYPHENYLALKYLPHOSPHORIC ESTER | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0785967-A1 | INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES | Ciba SC Holding AG (CH) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011978-A1 | INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1996-04-25 | — | — | WO | disclosed |