Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | IL2 | P60568 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19287365 | 0.82 | KDM4E (0.43) | LMNAHTTMAPTHRH3CYP2D6 | |
| SCHEMBL20409590 | 0.81 | KDM4E (0.53) | LMNAHTTMAPTHRH3CYP2D6 | |
| SCHEMBL471858 | 0.80 | KDM4E (0.60) | LMNAHTTMAPTHRH3CYP2D6 | |
| SCHEMBL4472084 | 0.80 | HTT (0.52) | LMNAHTTMAPTHRH3CYP2D6 | |
| SCHEMBL20411007 | 0.79 | HRH3 (0.54) | LMNAHTTMAPTHRH3CYP2D6 | |
| SCHEMBL2088974 | 0.79 | KDM4E (0.51) | LMNAHTTMAPTHRH3CYP2D6 | |
| SCHEMBL8901428 | 0.78 | ESR1 (0.50) | LMNAHTTMAPTHRH3CYP2D6 | |
| SCHEMBL2089146 | 0.76 | KDM4E (0.53) | LMNAHTTMAPTHRH3CYP2D6 | |
| SCHEMBL4447566 | 0.76 | KDM4E (0.51) | LMNAHTTMAPTHRH3CYP2D6 | |
| SCHEMBL10837608 | 0.76 | KDM4E (0.56) | LMNAHTTMAPTHRH3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377724-B2 | Aryl halide cross-coupling method and product made therefrom | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2019-08-13 | — | — | US | disclosed |
| US-10377723-B2 | Solid-supported catalyst for cross-coupling | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2019-08-13 | — | — | US | disclosed |
| US-20190161458-A1 | ARYL HALIDE CROSS-COUPLING METHOD AND PRODUCT MADE THEREFROM | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2019-05-30 | — | — | US | disclosed |
| US-20190161457-A1 | SOLID-SUPPORTED CATALYST FOR CROSS-COUPLING | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2019-05-30 | — | — | US | disclosed |
| US-10280147-B2 | Solid-supported palladium (II) complex as a heterogeneous catalyst for cross coupling reactions and methods thereof | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2019-05-07 | — | — | US | disclosed |
| US-20170275318-A1 | SOLID-SUPPORTED PALLADIUM (II) COMPLEX AS A HETEROGENEOUS CATALYST FOR CROSS COUPLING REACTIONS AND METHODS THEREOF | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275318-A1 | SOLID-SUPPORTED PALLADIUM (II) COMPLEX AS A HETEROGENEOUS CATALYST FOR CROSS COUPLING REACTIONS AND METHODS THEREOF | SIK1, SIK2, ULK2 | LMNA 4848/4885HTT 1131/4885MAPT 3340/4885 |
| US-20190161458-A1 | ARYL HALIDE CROSS-COUPLING METHOD AND PRODUCT MADE THEREFROM | ITK, SHPRH, SYMPK | LMNA 4876/4885HTT 472/4885MAPT 3850/4885 |
| US-10377723-B2 | Solid-supported catalyst for cross-coupling | SIK1, SIK2, SGK1 | LMNA 4853/4885HTT 838/4885MAPT 3549/4885 |
| US-20190161457-A1 | SOLID-SUPPORTED CATALYST FOR CROSS-COUPLING | SIK1, SIK2, SGK1 | LMNA 4853/4885HTT 838/4885MAPT 3549/4885 |
| US-10377724-B2 | Aryl halide cross-coupling method and product made therefrom | ITK, SHPRH, SYMPK | LMNA 4876/4885HTT 472/4885MAPT 3850/4885 |
| US-10280147-B2 | Solid-supported palladium (II) complex as a heterogeneous catalyst for cross coupling reactions and methods thereof | SIK1, SIK2, ULK2 | LMNA 4848/4885HTT 1131/4885MAPT 3340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.