Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459720 | 0.77 | HCAR2 (0.33) | HCAR2HCAR3 | |
| SCHEMBL4459796 | 0.73 | HCAR2 (0.35) | HCAR2HCAR3 | |
| SCHEMBL4466040 | 0.69 | — | — | |
| SCHEMBL4459601 | 0.69 | HCAR2 (0.34) | HCAR2HCAR3 | |
| SCHEMBL4454785 | 0.68 | — | — | |
| SCHEMBL4282740 | 0.65 | — | — | |
| SCHEMBL2449904 | 0.64 | — | — | |
| SCHEMBL1269500 | 0.63 | — | — | |
| SCHEMBL4459321 | 0.62 | PDE8B (0.31) | — | |
| SCHEMBL2846014 | 0.62 | BACE1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009017838-A2 | COMBINATIONS OF JAK-2 INHIBITORS AND OTHER AGENTS | EXELIXIS, INC. (US) | 2009-02-05 | — | — | WO | claimed |
| WO-2009017838-A2 | COMBINATIONS OF JAK-2 INHIBITORS AND OTHER AGENTS | EXELIXIS, INC. (US) | 2009-02-05 | — | — | WO | disclosed |