Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472550 | 0.77 | HCAR2 (0.33) | HCAR2HCAR3 | |
| SCHEMBL4464333 | 0.71 | IGF1R (0.40) | — | |
| SCHEMBL4459601 | 0.66 | HCAR2 (0.34) | HCAR2HCAR3 | |
| SCHEMBL4473250 | 0.63 | HCAR2 (0.33) | HCAR2HCAR3 | |
| SCHEMBL1269500 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL21929877 | 0.61 | HCAR2 (0.47) | HCAR2HCAR3 | |
| SCHEMBL4460989 | 0.61 | FGFR2 (0.34) | — | |
| SCHEMBL786337 | 0.57 | HCAR2 (0.50) | HCAR2HCAR3 | |
| SCHEMBL19400917 | 0.55 | — | — | |
| SCHEMBL20681842 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009017838-A2 | COMBINATIONS OF JAK-2 INHIBITORS AND OTHER AGENTS | EXELIXIS, INC. (US) | 2009-02-05 | — | — | WO | disclosed |