SCHEMBL4473338

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4475217	0.88	HPGD (0.52)	HSD17B10ALDH1A1CNR1NPSR1KMT2A
	SCHEMBL4481337	0.84	SMN1; SMN2 (0.58)	ALDH1A1NPSR1KMT2AMEN1TSHR
	SCHEMBL12792444	0.81	HSD17B10 (0.59)	HSD17B10ALDH1A1NPSR1KMT2AMEN1
	SCHEMBL11116524	0.81	HSD17B10 (0.89)	HSD17B10ALDH1A1NPSR1KMT2AMEN1
	SCHEMBL168000	0.81	HTT (0.56)	HSD17B10ALDH1A1CNR1NPSR1KMT2A
	SCHEMBL12081963	0.79	SMN1; SMN2 (0.58)	HSD17B10ALDH1A1CNR1NPSR1KMT2A
	SCHEMBL2932586	0.78	HSD17B10 (0.58)	HSD17B10ALDH1A1NPSR1KMT2AMEN1
	SCHEMBL168475	0.78	HSD17B10 (0.53)	HSD17B10ALDH1A1CNR1NPSR1KMT2A
	SCHEMBL168737	0.78	HSD17B10 (0.53)	HSD17B10ALDH1A1CNR1NPSR1KMT2A
	SCHEMBL166546	0.78	HSD17B10 (0.50)	HSD17B10ALDH1A1NPSR1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.