SCHEMBL4473810

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4460125	1.00	CCR5 (0.58)	CCR5CACNA2D1CACNB1CACNA1ACACNA1C
	SCHEMBL4460130	1.00	CCR5 (0.58)	CCR5CACNA2D1CACNB1CACNA1ACACNA1C
	SCHEMBL4475599	0.93	CCR5 (0.52)	CCR5CACNA2D1CACNB1CACNA1ACACNA1C
	SCHEMBL4475596	0.93	CCR5 (0.52)	CCR5CACNA2D1CACNB1CACNA1ACACNA1C
	SCHEMBL4460215	0.93	CCR5 (0.55)	CCR5CACNA2D1CACNB1CACNA1ACACNA1C
	SCHEMBL4460220	0.93	CCR5 (0.55)	CCR5CACNA2D1CACNB1CACNA1ACACNA1C
	SCHEMBL4465801	0.93	CCR5 (0.55)	CCR5CACNA2D1CACNB1CACNA1ACACNA1C
	SCHEMBL4475768	0.91	CACNA2D1 (0.57)	CCR5CACNA2D1CACNB1CACNA1CCACNA1B
	SCHEMBL4477780	0.91	CACNA2D1 (0.57)	CCR5CACNA2D1CACNB1CACNA1CCACNA1B
	SCHEMBL4475771	0.91	CACNA2D1 (0.57)	CCR5CACNA2D1CACNB1CACNA1CCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.