Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 1.00 |
| ▸ | PDE4A | P27815 | 1/20 | 1.00 |
| ▸ | PDE4B | Q07343 | 1/20 | 1.00 |
| ▸ | PDE4C | Q08493 | 1/20 | 1.00 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204721 | 1.00 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CMCHR1 | |
| Pumafentrine SCHEMBL8344522 | 1.00 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CMCHR1 | |
| Pumafentrine SCHEMBL26718 | 1.00 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CMCHR1 | |
| Pumafentrine SCHEMBL29651667 | 1.00 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CMCHR1 | |
| Pumafentrine SCHEMBL5187632 | 0.99 | PDE4D (0.98) | PDE4DPDE4APDE4BPDE4CMCHR1 | |
| Hydrochloric Acid SCHEMBL8388626 | 0.99 | PDE4D (0.98) | PDE4DPDE4APDE4BPDE4CMCHR1 | |
| Pumafentrine SCHEMBL5187638 | 0.99 | PDE4D (0.98) | PDE4DPDE4APDE4BPDE4CMCHR1 | |
| Hydrochloric Acid SCHEMBL8388627 | 0.99 | PDE4D (0.98) | PDE4DPDE4APDE4BPDE4CMCHR1 | |
| SCHEMBL7204406 | 0.97 | PDE4D (0.94) | PDE4DPDE4APDE4BPDE4CMCHR1 | |
| SCHEMBL7204724 | 0.97 | PDE4D (0.94) | PDE4DPDE4APDE4BPDE4CMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222193-A1 | Novel combination for the treatment of airway disorders | ALTANA PHARMA AG (DE) | 2005-10-06 | — | — | US | claimed |
| US-20050165041-A1 | Combination for the treatment of airway disorders | ALTANA PHARMA AG (DE) | 2005-07-28 | — | — | US | claimed |
| EP-1517706-A2 | COMBINATION OF A PROTON PUMP INHIBITOR AND A RESPIRATORY AGENT FOR THE TREATMENT OF RESPIRATORY DISEASES | ALTANA Pharma AG (DE) | 2005-03-30 | — | — | EP | claimed |
| WO-2003094968-A2 | COMBINATION OF A PROTON PUMP INHIBITOR AND A RESPIRATORY AGENT FOR THE TREATMENT OF RESPIRATORY DISEASES | ALTANA PHARMA AG (DE) | 2003-11-20 | — | — | WO | claimed |
| EP-0937074-B1 | BENZONAPHTHYRIDINES AS BRONCHIAL THERAPEUTICS | ALTANA PHARMA AG (DE) | 2003-03-12 | — | — | EP | claimed |
| US-6008215-A | TREATING INFLAMMATORY AIRWAY DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-12-28 | — | — | US | claimed |
| US-11555040-B2 | Oxepinopyrazole derivatives as inhibitors of P13-kinase activity | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-01-17 | — | — | US | disclosed |
| US-20220324875-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-10-13 | — | — | US | disclosed |
| EP-1907037-B2 | MEDICAMENT DISPENSER | GLAXO GROUP LTD (GB) | 2022-09-07 | — | — | EP | disclosed |
| EP-1962932-B1 | MEDICAMENT DISPENSER | GLAXO GROUP LTD (GB) | 2021-09-08 | — | — | EP | disclosed |
| EP-3260453-B1 | OXAZOLE SUBSTITUTED INDAZOLES AS PI3-KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2021-03-31 | — | — | EP | disclosed |
| EP-3414228-B1 | CHEMICAL COMPOUNDS AS INHIBITORS OF KINASE ACTIVITY | GLAXOSMITHKLINE IP DEV LTD (GB) | 2020-03-18 | — | — | EP | disclosed |
| EP-1907037-B1 | MEDICAMENT DISPENSER | GLAXO GROUP LTD (GB) | 2019-07-17 | — | — | EP | disclosed |
| WO-2003094967-A2 | NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS | ALTANA PHARMA AG (DE) | 2003-11-20 | — | — | WO | disclosed |
| WO-2003094968-A2 | COMBINATION OF A PROTON PUMP INHIBITOR AND A RESPIRATORY AGENT FOR THE TREATMENT OF RESPIRATORY DISEASES | ALTANA PHARMA AG (DE) | 2003-11-20 | — | — | WO | disclosed |
| EP-1341527-A1 | PHARMACEUTICAL PREPARATION COMPRISING AN ACTIVE DISPERSED ON A MATRIX | ALTANA Pharma AG (DE) | 2003-09-10 | — | — | EP | disclosed |
| WO-2003024488-A2 | COMBINATION OF A PDE INHIBITOR AND A LEUKOTRIENE RECEPTOR ANTAGONIST | ALTANA PHARMA AG (DE) | 2003-03-27 | — | — | WO | disclosed |
| EP-0937074-B1 | BENZONAPHTHYRIDINES AS BRONCHIAL THERAPEUTICS | ALTANA PHARMA AG (DE) | 2003-03-12 | — | — | EP | disclosed |
| WO-2002045693-A1 | PHARMACEUTICAL PREPARATION COMPRISING AN ACTIVE DISPERSED ON A MATRIX | ALTANA PHARMA AG (DE) | 2002-06-13 | — | — | WO | disclosed |
| US-6008215-A | TREATING INFLAMMATORY AIRWAY DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220324875-A1 | CHEMICAL COMPOUNDS | PIK3CA, PIK3CD, PIK3CB | PDE4D 1068/4885PDE4A 1096/4885PDE4B 844/4885 |
| US-11555040-B2 | Oxepinopyrazole derivatives as inhibitors of P13-kinase activity | CDK3, CDK13, AKT3 | PDE4D 547/4885PDE4A 576/4885PDE4B 716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.