SCHEMBL447463

SCHEMBL447463

CCC(O)Nc1ccc(C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
MMP8 P22894 1/20 0.47
ALDH1A1 P00352 5/20 0.46
TDP1 Q9NUW8 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
HSP90AA1 P07900 2/20 0.46
THRB P10828 2/20 0.46
ALOX15 P16050 2/20 0.46
CASP1 P29466 2/20 0.46
HSD17B10 Q99714 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
HIF1A Q16665 1/20 0.46
MAPT P10636 4/20 0.43
POLB P06746 2/20 0.42
HPGD P15428 3/20 0.38
MEN1 O00255 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8907855 0.81 CA12 (0.46) CA12ALDH1A1TDP1SMN1; SMN2HSP90AA1
SCHEMBL14532077 0.81 CYP3A4 (0.45) ALDH1A1TDP1SMN1; SMN2HSP90AA1THRB
SCHEMBL445994 0.81 TDP1 (0.45) CA12CA1ALDH1A1TDP1SMN1; SMN2
SCHEMBL31265919 0.81 ALDH1A1 (0.75) CA12CA1ALDH1A1TDP1SMN1; SMN2
SCHEMBL347685 0.80 TDP1 (0.50) CA12ALDH1A1TDP1SMN1; SMN2HSP90AA1
SCHEMBL27928253 0.78 TDP1 (0.48) CA12ALDH1A1TDP1SMN1; SMN2HSP90AA1
Ammonia Solution, Strong SCHEMBL27928251 0.78 TDP1 (0.48) CA12ALDH1A1TDP1SMN1; SMN2HSP90AA1
Hydrochloric Acid SCHEMBL5962620 0.78 TDP1 (0.48) CA12ALDH1A1TDP1SMN1; SMN2HSP90AA1
Hydrochloric Acid SCHEMBL29730240 0.78 TDP1 (0.48) CA12ALDH1A1TDP1SMN1; SMN2HSP90AA1
SCHEMBL28635453 0.78 ALDH1A1 (0.50) CA12CA1ALDH1A1TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421794-B1 REFRIGERATION APPARATUS DAIKIN IND LTD (JP) 2020-08-05 EP claimed
EP-3421794-A1 REFRIGERATION APPARATUS Daikin Industries, Ltd. (JP) 2019-01-02 EP claimed
EP-0361408-B1 Improved bone cement WOLLF & KAABER AS (DK) 1993-11-24 EP claimed
EP-0407124-A1 Lubricating oil composition Tonen Corporation (JP) 1991-01-09 EP claimed
WO-2024143180-A1 LUBRICATING OIL COMPOSITION 出光興産株式会社 2024-07-04 WO disclosed
US-20240218226-A1 REFRIGERATION CYCLE DEVICE FOR VEHICLE DAIKIN INDUSTRIES, LTD. (JP) 2024-07-04 US disclosed
US-20240174905-A1 REFRIGERANT CYCLE APPARATUS DAIKIN INDUSTRIES, LTD. (JP) 2024-05-30 US disclosed
US-11920077-B2 Refrigeration cycle device for vehicle DAIKIN INDUSTRIES, LTD. (JP) 2024-03-05 US disclosed
US-11912922-B2 Refrigerant cycle apparatus DAIKIN INDUSTRIES, LTD. (JP) 2024-02-27 US disclosed
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
EP-4234293-A2 REFRIGERATION CYCLE DEVICE FOR VEHICLE Daikin Industries, Ltd. (JP) 2023-08-30 EP disclosed
EP-4230707-A1 REFRIGERANT CYCLE APPARATUS Daikin Industries, Ltd. (JP) 2023-08-23 EP disclosed
EP-1063279-A1 Refrigerator oil for carbon dioxide refrigerant, and method of using it for lubrication Idemitsu Kosan Co., Ltd. (JP) 2000-12-27 EP disclosed
EP-1052281-A1 NOVEL ADDITIVE COMPOSITIONS IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-11-15 EP disclosed
US-6136759-A OIL ADDITIVE COMPOSITION COMPRISING ESTER COMPOUND, EXTREME PRESSURE IMPROVER CONTAINING SULFUR AND IMPROVER CONTAINING PHOSPHORUS IDEMITSU KOSAN CO., LTD. (JP) 2000-10-24 US disclosed
EP-1008643-A2 Refrigerator oil composition, and method of using the composition for lubrication IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-06-14 EP disclosed
US-5972854-A PREVENTS BRAKE LINING OF CLUTCH OF AUTOMATIC TRANSMISSIONS FROM SHUDDERING IDEMITSU KOSAN CO., LTD. (JP) 1999-10-26 US disclosed
EP-0812900-A2 Lubricating oil composition for automatic transmission IDEMITSU KOSAN COMPANY LIMITED (JP) 1997-12-17 EP disclosed
US-5391307-A Lubricating oil composition TONEN CORP. (JP) 1995-02-21 US disclosed
EP-0407124-A1 Lubricating oil composition Tonen Corporation (JP) 1991-01-09 EP disclosed